Do We Need Yet Another Hybrid Imaging Device?

Vascular remodeling: do we really need yet another study?

More than 15 years have passed since Seymour Glagov published his seminal article describing the phenomenon of vascular remodeling which now bears his name (1). By meticulously examining finely sectioned left main coronary arteries from necropsy specimens, he observed a change in the arterial size that was proportional to the plaque burden. This simple observation had profound implications. The...

Do we need another Kt/V?

A new method of estimating Kt/V has been proposed. This was a required update to accommodate frequencies of dialysis other than thrice weekly [1].The original approximate method for calculating Kt/V from preand post-dialysis urea concentrations was developed using linear regression on a data set of measurements taken from patients undergoing thrice-weekly dialysis. The method assumes that the i...

Rosuvastatin: do we need another statin?

(1) Rosuvastatin (Crestor(TM)) is a new synthetic agent for the treatment and prevention of lipid disorders, a risk factor for coronary heart disease. (2) Rosuvastatin is undergoing phase III clinical trials. A New Drug Application was submitted to the U.S. Food and Drug Administration in June, 2001. No information on the regulatory status in Canada is currently available. (3) Limited evidence ...

Why We Do Need Another Medical Journal…

The English word "health" comes from the Old English word hale, meaning "wholeness, a state of being and feeling whole, sound or well" [1]. Hale comes from the Proto-Indo-European root "kailo", meaning "whole, uninjured, of good omen". Kailo comes from the Proto-Germanic root "khalbas", meaning "something (un)divided". [...].

Salt wars: do we need another episode?